nitric oxide-cGMP-mediated signaling

Term ID

GO:0038060

Synonyms

• canonical nitric oxide signaling
• classical nitric oxide signaling
• nitric oxide-cGMP-mediated signal transduction
• nitric oxide-cGMP-mediated signaling pathway
• nitric oxide-cGMP-mediated signalling pathway
• NO-cGMP signaling pathway

Definition

An intracellular signaling cassette in which the signal is passed on within the cell by nitric oxide (NO) activating soluble guanylyl cyclase (sGC). Includes synthesis of nitric oxide, guanylyl cyclase activity, and downstream effectors that further transmit the signal within the cell following activation by cGMP. (2)

References

Ontology

GO: Biological Process    QuickGO    AmiGO