Search Ontology:
GO: Cellular Component

TCR signalosome

Term ID
GO:0036398
Synonyms
  • LAT signalosome
  • linker for activation of T cells signalosome
Definition
A multi-protein complex containing at least the T-cell receptor complex and the LAT (linker for activation of T cells) scaffold protein. Also contains a variety of signaling proteins including co-receptors, kinases, phosphatases and adaptors such as CD8. Connects events on the plasma membrane to distal signaling cascades to ultimately modulate T cell biology. (3)
References
Ontology
GO: Cellular Component    QuickGO    AmiGO
Relationships
is a type of
has_part
Phenotype
Phenotype caused by Genes