Cdc48p-Npl4p-Vms1p AAA ATPase complex

Term ID

GO:0036266

Synonyms

• Cdc48p-Npl4p-Vms1p complex
• Vms1-Cdc48-Npl4 complex
• Vms1p-Cdc48p-Npl4p complex

Definition

A multiprotein ATPase complex involved in the release of polyubiquitinated proteins, including those damaged by oxidative stress, from the outer mitochondria membrane into the cytoplasm where they are presented to the proteasome for proteolysis, a process also referred to as mitochondria-associated degradation (MAD). In budding yeast, this complex includes Cdc48p, Npl4p and Vms1p. (2)

References

Ontology

GO: Cellular Component    QuickGO    AmiGO