Search Ontology:
GO: Biological Process

interleukin-4-dependent isotype switching to IgE isotypes

Term ID
GO:0035708
Synonyms
  • IL-4-dependent isotype switching to IgE isotypes
Definition
The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus, that is dependent on the activity of interleukin 4 (IL-4). 12496423
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
is a type of
positively regulated by
regulated by
Phenotype
Phenotype caused by Genes
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