MH2 domain binding

Term ID

GO:0035500

Synonyms

• MAD homology 2 domain binding

Definition

Binding to a MH2 (MAD homology 2) protein domain. The MH2 domain is found at the carboxy-terminus of MAD related proteins such as Smads. The MH2 domain mediates interaction with a wide variety of proteins and provides specificity and selectivity to Smad function and also is critical for mediating interactions in Smad oligomers.

References

Ontology

GO: Molecular Function    QuickGO    AmiGO