Roundabout signaling pathway

Term ID

GO:0035385

Synonyms

ROBO signaling pathway
ROBO/SLIT signaling pathway
Roundabout signalling pathway

Definition

The series of molecular signals initiated by a SLIT protein binding to a Roundabout (ROBO) family receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.

References

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

has parts: termination of Roundabout signal transduction

termination of Roundabout signal transduction Show first 5 Terms
is a type of: cell surface receptor signaling pathway

cell surface receptor signaling pathway Show first 5 Terms
has subtype: Roundabout signaling pathway involved in axon guidance Roundabout signaling pathway involved in muscle cell chemotaxis toward tendon cell

Roundabout signaling pathway involved in axon guidance Roundabout signaling pathway involved in muscle cell chemotaxis toward tendon cell Show first 5 Terms
negatively regulated by: negative regulation of Roundabout signaling pathway

negative regulation of Roundabout signaling pathway Show first 5 Terms
positively regulated by: positive regulation of Roundabout signaling pathway

positive regulation of Roundabout signaling pathway Show first 5 Terms
regulated by: regulation of Roundabout signaling pathway

regulation of Roundabout signaling pathway Show first 5 Terms

Phenotype

Phenotype caused by Genes