NuA4 histone acetyltransferase complex

Term ID

GO:0035267

Synonyms

• TIP60 histone acetylase complex
• TIP60 histone acetyltransferase complex

Definition

A complex having histone acetylase activity on chromatin, as well as ATPase, DNA helicase and structural DNA binding activities. The complex is thought to be involved in double-strand DNA break repair. Subunits of the human complex include HTATIP/TIP60, TRRAP, RUVBL1, BUVBL2, beta-actin and BAF53/ACTL6A. In yeast, the complex has 13 subunits, including the catalytic subunit Esa1 (homologous to human Tip60). (2)

References

Ontology

GO: Cellular Component    QuickGO    AmiGO