CFTR-NHERF-ezrin complex

Term ID

GO:0034662

Synonyms

Definition

A protein complex that contains ezrin, Na+/H+ exchanger regulatory factor (NHERF, also called EBP50), and two copies of the cystic fibrosis transmembrane conductance regulator (CFTR). The CFTR molecules interact with NHERF via their cytoplasmic tail domains; the complex is thought to link the CFTR channel to the actin cytoskeleton and contribute to the regulation of channel activity. (3)

References

Ontology

GO: Cellular Component    QuickGO    AmiGO