conversion of discoidal high-density lipoprotein particle to spherical high-density lipoprotein particle

Term ID

GO:0034376

Synonyms

• conversion of discoidal HDL to spherical HDL
• discoidal HDL remodeling
• discoidal high-density lipoprotein remodeling

Definition

The process in which a discoidal high-density lipoprotein (HDL) particle acquires additional lipid or protein molecules, and cholesterol in the particle is converted to tightly bound cholesterol esters by the action of phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT), resulting in the formation of a spherical HDL particle.

References

Ontology

GO: Biological Process    QuickGO    AmiGO