Search Ontology:
GO: Molecular Function

25-hydroxycholesterol 7alpha-hydroxylase activity

Term ID
GO:0033783
Synonyms
  • 25-hydroxycholesterol 7alpha-monooxygenase activity
  • cholest-5-ene-3beta,25-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity
  • CYP7B1
  • CYP7B1 oxysterol 7alpha-hydroxylase activity
Definition
Catalysis of the reactions: 25-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] = 7alpha,25-dihydroxycholesterol + H+ + H2O + oxidized [NADPH--hemoprotein reductase]. Also converts (25R)-cholest-5-ene-3beta,26-diol to (25R)-cholest-5-en-3beta,7alpha,26-triol. 1.14.14.29
References
Ontology
GO: Molecular Function    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes
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