24S-hydroxycholesterol 7-alpha-hydroxylase activity

Term ID

GO:0033782

Synonyms

24-cholest-5-ene-3beta,24-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity
24-hydroxycholesterol 7alpha-hydroxylase activity
24-hydroxycholesterol 7alpha-monooxygenase activity

Definition

Catalysis of the reaction: (24S)-hydroxycholesterol + O2 + reduced [NADPH-hemoprotein reductase] = (24S)-7alpha-dihydroxycholesterol + H+ + H2O + oxidized [NADPH-hemoprotein reductase]. (2)

References

EC:1.14.14.26
KEGG_REACTION:R07208
MetaCyc:1.14.13.99-RXN
RHEA:46124

Ontology

GO: Molecular Function QuickGO AmiGO

Relationships

is a type of: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen steroid 7-alpha-hydroxylase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen steroid 7-alpha-hydroxylase activity Show first 5 Terms

Phenotype

Phenotype caused by Genes