Search Ontology:

GO: Molecular Function

cholesterol 24-hydroxylase activity

Term ID

GO:0033781

Synonyms

cholesterol 24-monooxygenase activity
cholesterol 24S-hydroxylase activity
cholesterol,NADPH:oxygen oxidoreductase (24-hydroxylating) activity
CYP46
CYP46A1
cytochrome P450 46A1

Definition

Catalysis of the reaction: cholesterol + H+ + NADPH + O2 = (24S)-24-hydroxycholesterol + H2O + NADP+. 1.14.14.25

References

EC:1.14.14.25
KEGG_REACTION:R07207
MetaCyc:1.14.13.98-RXN
RHEA:22716
Reactome:R-HSA-192061

Ontology

GO: Molecular Function QuickGO AmiGO

Relationships

is a type of: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen Show first 5 Terms

Phenotype

Phenotype caused by Genes