Search Ontology:
GO: Molecular Function

peptide-methionine (R)-S-oxide reductase activity

Term ID
GO:0033743
Synonyms
  • methionine S-oxide reductase (R-form oxidizing) activity
  • methionine S-oxide reductase activity
  • methionine sulfoxide reductase activity
  • methionine sulfoxide reductase B activity
  • MsrB
  • peptide-methionine:thioredoxin-disulfide S-oxidoreductase [methionine (R)-S-oxide-forming] activity
  • PilB
  • pMRsr
  • pMSR
  • protein-methionine-R-oxide reductase activity
  • selenoprotein R
  • SelR
  • SelX
Definition
Catalysis of the reaction: peptide-L-methionine + H2O + thioredoxin disulfide = peptide-L-methionine (R)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the R enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin. 1.8.4.12
References
  • EC:1.8.4.12
  • KEGG_REACTION:R07607
  • MetaCyc:1.8.4.12-RXN
  • RHEA:24164
  • Reactome:R-HSA-5676917
Ontology
GO: Molecular Function    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes