Rpd3L complex

Term ID

GO:0033698

Synonyms

• Clr6 histone deacetylase complex I/I'
• Clr6L complex
• Rpd3C(L)
• Sin3L complex

Definition

A histone deacetylase complex which deacetylates histones preferentially in promoter regions. Composed of a two copies of catalytic histone deacetylase subunit (S. pombe Clr6/ S. cerevisiae Rpd3p), an Sds-3 family protein (S. pombe /S. cerevisiae Sds3(p) ), two copies of SIN3 family co-repressor (S. pombe Pst1/ S. cerevisiae Sin3p, a WD repeat protein/ histone chaperone (S. pombe Prw1/ S. cerevisiae Ume1p), and a zf- PHD finger ( S. pombe Png2/ S. cerevisiae Pho23p), plus 4 additional subunits, and associated factors. 17450151

References

Ontology

GO: Cellular Component    QuickGO    AmiGO