Search Ontology:
GO: Cellular Component

eukaryotic 48S preinitiation complex

Term ID
GO:0033290
Synonyms
  • eukaryotic 48S initiation complex
  • eukaryotic 48S pre-initiation complex
Definition
The protein-ribosome-tRNA complex that has just recognized the start codon of a capped mRNA. It is composed of the small ribosomal subunit, eukaryote initiation factors (eIF) eIF3 complex, eIF1, eIF1A, eIF2-GDP, eIF4 complex and initiatior-methionine-tRNA. Recognition of the start codon triggers downstream steps in the pathway, including eIF1 dissociation; Pi release from eIF2; and conversion to the closed, scanning-arrested conformation of the PIC. (4)
References
Ontology
GO: Cellular Component    QuickGO    AmiGO
Relationships
is a type of
has_part
Phenotype
Phenotype caused by Genes
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