Search Ontology:
GO: Biological Process

SREBP signaling pathway

Term ID
GO:0032933
Synonyms
  • activation of sterol regulatory element binding protein target gene transcription
  • endoplasmic reticulum to nucleus sterol response pathway
  • endoplasmic reticulum-nuclear sterol response pathway
  • ER to nucleus sterol response pathway
  • ER-nuclear sterol response pathway
  • positive regulation of sterol regulatory element binding protein target gene transcription
  • positive regulation of sterol regulatory element binding protein target gene transcription involved in sterol depletion response
  • positive regulation of transcription via sterol regulatory element binding
  • positive regulation of transcription via sterol regulatory element binding involved in ER-nuclear sterol response pathway
  • SREBP signalling
  • SREBP target gene transcriptional activation
  • SREBP-mediated signaling pathway
  • SREBP-mediated signalling pathway
  • sterol depletion response, SREBP target gene transcriptional activation
  • sterol regulatory element binding protein target gene transcriptional activation
  • sterol response element binding protein signaling pathway
  • stimulation of sterol regulatory element binding protein target gene transcription
  • up regulation of sterol regulatory element binding protein target gene transcription
  • up-regulation of sterol regulatory element binding protein target gene transcription
  • upregulation of sterol regulatory element binding protein target gene transcription
Definition
The series of molecular signals from the endoplasmic reticulum to the nucleus generated as a consequence of decreased levels of one or more sterols (and in some yeast, changes in oxygen levels) and which proceeds through activation of a sterol response element binding transcription factor (SREBP) to result in up-regulation of target gene transcription. (2)
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
is a type of
negatively regulated by
positively regulated by
regulated by
Phenotype
Phenotype caused by Genes