Search Ontology:
GO: Biological Process
tumor necrosis factor production
- Term ID
- GO:0032640
- Synonyms
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- cachectin production
- TNF alpha biosynthesis
- TNF biosynthesis
- TNF biosynthetic process
- TNF production
- TNF-alpha biosynthesis
- TNF-alpha biosynthetic process
- TNF-alpha production
- Tnfa production
- tumor necrosis factor anabolism
- tumor necrosis factor biosynthesis
- tumor necrosis factor biosynthetic process
- tumor necrosis factor formation
- tumor necrosis factor secretion
- tumor necrosis factor synthesis
- tumor necrosis factor-alpha production
- Definition
- The appearance of tumor necrosis factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Tumor necrosis factor is an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis. (2)
- References
- Ontology
- GO: Biological Process QuickGO AmiGO
- is a type of
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- inverse capable_of
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- negatively regulated by
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- positively regulated by
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- regulated by
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Phenotype
Phenotype caused by Genes