Search Ontology:
GO: Cellular Component

nuclear pore outer ring

Term ID
GO:0031080
Synonyms
  • Nup107-120 complex
  • Nup107-160 complex
  • Nup84 complex
Definition
A subcomplex of the nuclear pore complex (NPC) that forms the outer rings of the core scaffold, a lattice-like structure that gives the NPC its shape and strength. In S. cerevisiae, the two outer rings each contain multiple copies of the following proteins: Nup133p, Nup120p, Nup145Cp, Nup85p, Nup84p, Seh1p, and Sec13p. In vertebrates, the two outer rings each contain multiple copies of the following proteins: Nup133, Nup160, Nup96, Nup75, Nup107, Seh1, Sec13, Nup43, Nup37, and ALADIN. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometimes referred to as the Nup84 complex (S. cerevisiae) or the Nup107-160 complex (vertebrates). (4)
References
Ontology
GO: Cellular Component    QuickGO    AmiGO
Relationships
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Phenotype
Phenotype caused by Genes