retromer, cargo-selective complex

Term ID

GO:0030906

Synonyms

• cargo-selective retromer subcomplex
• retromer complex, inner shell
• retromer CSC
• retromer, cargo recognition complex
• retromer, CRC

Definition

The trimeric subcomplex of the retromer, believed to be closely associated with the membrane. This trimeric complex is responsible for recognizing and binding to cargo molecules. The complex comprises three Vps proteins in both yeast and mammalian cells: Vps35p, Vps29p, and Vps26p in yeast, and VPS35, VPS29 and VPS26A or VPS26B in mammals. (3)

References

Ontology

GO: Cellular Component    QuickGO    AmiGO