Search Ontology:
GO: Cellular Component
AP-1 adaptor complex
- Term ID
- GO:0030121
- Synonyms
-
- AP-1 related adapter complex
- HA1
- HA1 clathrin adaptor
- Definition
- A heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C). (2)
- References
- Ontology
- GO: Cellular Component QuickGO AmiGO
- is part of
-
- is a type of
-
Phenotype
Phenotype caused by Genes