lipoate-protein ligase activity

Term ID

GO:0016979

Synonyms

• lipoate-protein ligase A activity
• lipoate-protein ligase activity (lipoylation of glycine cleavage complex)
• lipoate-protein ligase B activity

Definition

Catalysis of the lipoylation of a protein in two steps: ATP + (R)-lipoate + a [lipoyl-carrier protein]-L-lysine = a [lipoyl-carrier protein]-N6-(lipoyl)lysine + AMP + diphosphate (overall reaction): (1) ATP + (R)-lipoate = lipoyl-AMP + diphosphate; (2) lipoyl-AMP + a [lipoyl-carrier protein]-L-lysine = a [lipoyl-carrier protein]-N6-(lipoyl)lysine + AMP. (2)

References

• EC:6.3.1.20
• MetaCyc:RXN-17127
• RHEA:49288

Ontology

GO: Molecular Function    QuickGO    AmiGO