myotube differentiation

Term ID

GO:0014902

Synonyms

Definition

The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.

References

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

has parts: myoblast fusion myotube cell development

myoblast fusion myotube cell development Show first 5 Terms
is a type of: striated muscle cell differentiation

striated muscle cell differentiation Show first 5 Terms
has subtype: myotube differentiation involved in skeletal muscle regeneration skeletal muscle fiber differentiation

myotube differentiation involved in skeletal muscle regeneration skeletal muscle fiber differentiation Show first 5 Terms
negatively regulated by: negative regulation of myotube differentiation

negative regulation of myotube differentiation Show first 5 Terms
positively regulated by: positive regulation of myotube differentiation

positive regulation of myotube differentiation Show first 5 Terms
regulated by: regulation of myotube differentiation

regulation of myotube differentiation Show first 5 Terms

Phenotype

Phenotype caused by Genes