Search Ontology:
GO: Molecular Function
type I site-specific deoxyribonuclease activity
- Term ID
- GO:0009035
- Synonyms
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- adenosine triphosphate-dependent deoxyribonuclease activity
- ATP-dependent DNase activity
- deoxyribonuclease (adenosine triphosphate-hydrolyzing)
- deoxyribonuclease (ATP- and S-adenosyl-L-methionine-dependent)
- type I restriction enzyme activity
- Definition
- Catalysis of the endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5' or 3' protrusions, driven by ATP hydrolysis. Cleavage is dependent on the presence in the DNA of a specific recognition site. Cleavage may occur hundreds or thousands of base pairs away from the recognition site due to translocation of DNA. (2)
- References
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- EC:3.1.21.3
- MetaCyc:3.1.21.3-RXN
- Ontology
- GO: Molecular Function QuickGO AmiGO
- is a type of
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- regulated by
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Phenotype
Phenotype caused by Genes