Search Ontology:
GO: Cellular Component

inward rectifying potassium channel

Term ID
GO:0008282
Synonyms
  • ATP-sensitive potassium channel complex
  • inward rectifying K+ channel
  • KCNJ11-SUR complex
  • KCNJ11-SURx complex
  • KCNJ8-SUR complex
  • KCNJ8-SURx complex
  • Kir6-SUR complex
  • Kir6.1-SUR complex
  • Kir6.1-SURx complex
  • Kir6.2-SUR complex
  • Kir6.2-SURx complex
  • Kir6.x complex
  • Kir6.x-SURx complex
Definition
A protein complex that comprises four pore-forming (Kir6.x) and four regulatory sulphonylurea receptor (SURx) subunits and forms a transmembrane channel through which ions may pass. The opening and closing of the channel is regulated by ATP: binding of ATP to the Kir6.x subunit inhibits channel activity, whereas binding of Mg2+-complexed ATP or ADP to the SURx subunit stimulates channel activity. (2)
References
Ontology
GO: Cellular Component    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes