inward rectifying potassium channel

Term ID

GO:0008282

Synonyms

• ATP-sensitive potassium channel complex
• inward rectifying K+ channel
• KCNJ11-SUR complex
• KCNJ11-SURx complex
• KCNJ8-SUR complex
• KCNJ8-SURx complex
• Kir6-SUR complex
• Kir6.1-SUR complex
• Kir6.1-SURx complex
• Kir6.2-SUR complex
• Kir6.2-SURx complex
• Kir6.x complex
• Kir6.x-SURx complex

Definition

A protein complex that comprises four pore-forming (Kir6.x) and four regulatory sulphonylurea receptor (SURx) subunits and forms a transmembrane channel through which ions may pass. The opening and closing of the channel is regulated by ATP: binding of ATP to the Kir6.x subunit inhibits channel activity, whereas binding of Mg2+-complexed ATP or ADP to the SURx subunit stimulates channel activity. (2)

References

Ontology

GO: Cellular Component    QuickGO    AmiGO