Search Ontology:
GO: Biological Process

G protein-coupled receptor signaling pathway

Term ID
GO:0007186
Synonyms
  • dimeric G-protein coupled receptor signaling pathway
  • dimeric G-protein coupled receptor signalling pathway
  • G protein coupled receptor protein signaling pathway
  • G protein coupled receptor protein signalling pathway
  • G-protein coupled receptor protein signal transduction
  • G-protein coupled receptor protein signaling pathway
  • G-protein coupled receptor signaling pathway via GPCR dimer
  • G-protein coupled receptor signalling pathway
  • G-protein-coupled receptor protein signalling pathway
  • GPCR signaling pathway
  • GPCR signalling pathway
Definition
The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane. (3)
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
has parts
is a type of
has subtype
has_part
negatively regulated by
positively regulated by
regulated by
Phenotype
Phenotype caused by Genes