translational initiation

Term ID

GO:0006413

Synonyms

biopolymerisation
biopolymerization
protein synthesis initiation
translation initiation

Definition

The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA. 019879276X

References

Reactome:R-HSA-72613

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

is part of: translation

translation Show first 5 Terms
has parts: formation of translation initiation ternary complex methionyl-tRNA formyltransferase activity translation initiation factor activity

formation of translation initiation ternary complex methionyl-tRNA formyltransferase activity translation initiation factor activity Show first 5 Terms
is a type of: metabolic process

metabolic process Show first 5 Terms
has subtype: cytoplasmic translational initiation mitochondrial translational initiation

cytoplasmic translational initiation mitochondrial translational initiation Show first 5 Terms
has_part: formation of translation initiation ternary complex

formation of translation initiation ternary complex Show first 5 Terms
inverse has_part: translation

translation Show first 5 Terms
negatively regulated by: negative regulation of translation in response to oxidative stress negative regulation of translation initiation in response to endoplasmic reticulum stress negative regulation of translational initiation negative regulation of translational initiation in response to osmotic stress negative regulation of translational initiation in response to starvation ... Show All 6 Terms

negative regulation of translation in response to oxidative stress negative regulation of translation initiation in response to endoplasmic reticulum stress negative regulation of translational initiation negative regulation of translational initiation in response to osmotic stress negative regulation of translational initiation in response to starvation negative regulation of translational initiation in response to stress Show first 5 Terms
positively regulated by: positive regulation of translation initiation in response to endoplasmic reticulum stress positive regulation of translational initiation positive regulation of translational initiation in response to osmotic stress positive regulation of translational initiation in response to starvation positive regulation of translational initiation in response to stress

positive regulation of translation initiation in response to endoplasmic reticulum stress positive regulation of translational initiation positive regulation of translational initiation in response to osmotic stress positive regulation of translational initiation in response to starvation positive regulation of translational initiation in response to stress Show first 5 Terms
regulated by: regulation of translation initiation in response to endoplasmic reticulum stress regulation of translational initiation regulation of translational initiation in response to osmotic stress regulation of translational initiation in response to starvation regulation of translational initiation in response to stress

regulation of translation initiation in response to endoplasmic reticulum stress regulation of translational initiation regulation of translational initiation in response to osmotic stress regulation of translational initiation in response to starvation regulation of translational initiation in response to stress Show first 5 Terms

Phenotype

Phenotype caused by Genes