nucleotide-excision repair

Term ID

GO:0006289

Synonyms

intrastrand cross-link repair
NER
pyrimidine-dimer repair, DNA damage excision

Definition

A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts). 10197977

References

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

has parts: nucleotide-excision repair, DNA damage recognition nucleotide-excision repair, DNA damage removal nucleotide-excision repair, DNA duplex unwinding nucleotide-excision repair, DNA gap filling nucleotide-excision repair, preincision complex assembly ... Show All 6 Terms

nucleotide-excision repair, DNA damage recognition nucleotide-excision repair, DNA damage removal nucleotide-excision repair, DNA duplex unwinding nucleotide-excision repair, DNA gap filling nucleotide-excision repair, preincision complex assembly nucleotide-excision repair, preincision complex stabilization Show first 5 Terms
is a type of: DNA repair

DNA repair Show first 5 Terms
has subtype: global genome nucleotide-excision repair nucleotide-excision repair involved in interstrand cross-link repair pyrimidine dimer repair by nucleotide-excision repair transcription-coupled nucleotide-excision repair

global genome nucleotide-excision repair nucleotide-excision repair involved in interstrand cross-link repair pyrimidine dimer repair by nucleotide-excision repair transcription-coupled nucleotide-excision repair Show first 5 Terms
regulated by: regulation of nucleotide-excision repair

regulation of nucleotide-excision repair Show first 5 Terms

Phenotype

Phenotype caused by Genes