Search Ontology:
GO: Biological Process

lagging strand elongation

Term ID
GO:0006273
Synonyms
Definition
The process in which an existing DNA strand is extended in a net 3' to 5' direction by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication. Lagging strand DNA elongation proceeds by discontinuous synthesis of short stretches of DNA, known as Okazaki fragments, from RNA primers; these fragments are then joined by DNA ligase. Although each segment of nascent DNA is synthesized in the 5' to 3' direction, the overall direction of lagging strand synthesis is 3' to 5', mirroring the progress of the replication fork. (2)
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
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Phenotype
Phenotype caused by Genes