Search Ontology:
GO: Molecular Function
inward rectifier potassium channel activity
- Term ID
- GO:0005242
- Synonyms
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- Kir channel activity
- Definition
- Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. The inward-rectification is due to a voltage-dependent block of the channel pore by a specific ligand or ligands, and as a result the macroscopic conductance depends on the difference between membrane voltage and the K+ equilibrium potential rather than on membrane voltage itself. 14977398
- References
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- Reactome:R-HSA-1296045
- Reactome:R-HSA-1296046
- Reactome:R-HSA-1369017
- Reactome:R-HSA-5678261
- Reactome:R-HSA-5678418
- Reactome:R-HSA-9729870
- Reactome:R-HSA-9730521
- Reactome:R-HSA-9731072
- Ontology
- GO: Molecular Function QuickGO AmiGO
- is a type of
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- has subtype
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- negatively regulated by
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- positively regulated by
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- regulated by
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Phenotype
Phenotype caused by Genes