Search Ontology:
GO: Molecular Function

inward rectifier potassium channel activity

Term ID
GO:0005242
Synonyms
  • Kir channel activity
Definition
Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. The inward-rectification is due to a voltage-dependent block of the channel pore by a specific ligand or ligands, and as a result the macroscopic conductance depends on the difference between membrane voltage and the K+ equilibrium potential rather than on membrane voltage itself. 14977398
References
  • Reactome:R-HSA-1296045
  • Reactome:R-HSA-1296046
  • Reactome:R-HSA-1369017
  • Reactome:R-HSA-5678261
  • Reactome:R-HSA-5678418
  • Reactome:R-HSA-9729870
  • Reactome:R-HSA-9730521
  • Reactome:R-HSA-9731072
Ontology
GO: Molecular Function    QuickGO    AmiGO
Relationships
is a type of
has subtype
negatively regulated by
positively regulated by
regulated by
Phenotype
Phenotype caused by Genes