Search Ontology:
GO: Molecular Function

chemokine receptor activity

Term ID
GO:0004950
Synonyms
Definition
Combining with a chemokine, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria. (3)
References
Ontology
GO: Molecular Function    QuickGO    AmiGO
Relationships
is part of
is a type of
has subtype
has_part
Phenotype
Phenotype caused by Genes