nuclear receptor activity

Term ID

GO:0004879

Synonyms

• 1,25-(OH)2D3 receptor activity
• 9-cis retinoic acid receptor activity
• androgen receptor activity
• calcitriol receptor activity
• ecdysteroid hormone receptor activity
• glucocorticoid receptor activity
• juvenile hormone receptor activity
• ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
• ligand-dependent nuclear receptor activity
• ligand-dependent transcription factor activity
• nuclear hormone receptor
• retinoic acid receptor activity
• retinoid-X receptor activity
• RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
• RNA polymerase II transcription factor activity, glucocorticoid-activated sequence-specific DNA binding
• RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
• RXR
• thyroid hormone receptor activity
• vitamin A receptor activity
• vitamin D receptor activity
• vitamin D3 receptor activity

Definition

A DNA-binding transcription factor activity regulated by binding to a ligand that modulates the transcription of specific gene sets transcribed by RNA polymerase II. Nuclear receptor ligands are usually lipid-based (such as a steroid hormone) and the binding of the ligand to its receptor often occurs in the cytosol, which leads to its translocation to the nucleus. 23457262

References

Ontology

GO: Molecular Function    QuickGO    AmiGO