Search Ontology:
GO: Molecular Function

uracil DNA N-glycosylase activity

Term ID
GO:0004844
Synonyms
  • uracil-DNA glycosylase activity
Definition
Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases in DNA that result from the deamination of cytosine or the misincorporation of dUTP opposite an adenine. 9224623
References
  • EC:3.2.2.27
  • Reactome:R-HSA-110215
  • Reactome:R-HSA-110217
  • Reactome:R-HSA-9817512
Ontology
GO: Molecular Function    QuickGO    AmiGO
Relationships
is a type of
has subtype
Phenotype
Phenotype caused by Genes
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