ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor

Term ID

GO:0004748

Synonyms

• 2'-deoxyribonucleoside-diphosphate:oxidized-thioredoxin 2'-oxidoreductase activity
• 2'-deoxyribonucleoside-diphosphate:thioredoxin-disulfide 2'-oxidoreductase activity
• adenosylcobalamin-dependent ribonucleotide reductase activity
• aerobic non-heme iron-dependent ribonucleotide reductase activity
• anaerobic iron-sulfur-dependent ribonucleotide reductase activity
• class I ribonucleotide reductase activity
• class II ribonucleoside-diphosphate reductase activity
• class II ribonucleotide reductase activity
• class III ribonucleotide reductase activity
• nucleoside diphosphate reductase activity
• purine/pyrimidine nucleoside diphosphate reduction
• ribonucleoside 5'-diphosphate reductase activity
• ribonucleotide diphosphate reductase activity
• ribonucleotide reductase activity
• RNR

Definition

Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin. 1.17.4.1

References

• EC:1.17.4.1
• MetaCyc:RIBONUCLEOSIDE-DIP-REDUCTI-RXN
• RHEA:23252
• Reactome:R-HSA-111751
• Reactome:R-HSA-111804

Ontology

GO: Molecular Function    QuickGO    AmiGO