MAP kinase kinase activity

Term ID

GO:0004708

Synonyms

• ATP:protein phosphotransferase (MAPKKK-activated) activity
• ERK activator kinase activity
• MAP kinase kinase 4 activity
• MAP kinase kinase 7 activity
• MAP kinase or ERK kinase activity
• MAP2K
• MAPK activator activity
• MAPKK
• MAPKK activity
• MAPKK1
• MEK activity
• MEK1
• MEK2
• mitogen-activated protein kinase kinase activity
• MKK
• MKK2
• MKK4
• MKK6
• MKK7
• STK27

Definition

Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a T-X-Y motif in the activation loop of a MAP kinase (MAPK) substrate. (2)

References

• EC:2.7.12.2
• MetaCyc:2.7.12.2-RXN
• Reactome:R-HSA-1247960
• Reactome:R-HSA-3238999
• Reactome:R-HSA-448951
• Reactome:R-HSA-450333
• Reactome:R-HSA-5218804

Ontology

GO: Molecular Function    QuickGO    AmiGO