phosphoribosylformylglycinamidine synthase activity

Term ID

GO:0004642

Synonyms

• 2-N-formyl-1-N-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming)
• 5'-phosphoribosylformylglycinamide:L-glutamine amido-ligase (ADP-forming)
• FGAM synthase activity
• FGAM synthetase activity
• FGAR amidotransferase activity
• FGARAT activity
• formylglycinamide ribonucloetide amidotransferase activity
• formylglycinamide ribotide amidotransferase activity
• N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming)
• phosphoribosylformylglycinamidine synthetase activity
• phosphoribosylformylglycineamidine synthetase activity

Definition

Catalysis of the reaction: N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + ATP + H2O = 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate + ADP + 2 H+ + phosphate. 6.3.5.3

References

• EC:6.3.5.3
• KEGG_REACTION:R04463
• MetaCyc:FGAMSYN-RXN
• RHEA:17129
• Reactome:R-HSA-73812

Ontology

GO: Molecular Function    QuickGO    AmiGO