phosphoribosylformylglycinamidine cyclo-ligase activity

Term ID

GO:0004641

Synonyms

• 2-(formamido)-1-N-(5-phosphoribosyl)acetamidine cyclo-ligase (ADP-forming)
• 2-(formamido)-N1-(5-phosphoribosyl)acetamidine cyclo-ligase (ADP-forming)
• 5'-aminoimidazole ribonucleotide synthetase activity
• AIR synthase activity
• AIR synthetase activity
• AIRS activity
• phosphoribosyl-aminoimidazole synthetase activity
• phosphoribosylaminoimidazole synthetase activity

Definition

Catalysis of the reaction: 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + ATP = 5-amino-1-(5-phospho-D-ribosyl)imidazole + ADP + 2 H+ + phosphate. 6.3.3.1

References

• EC:6.3.3.1
• KEGG_REACTION:R04208
• MetaCyc:AIRS-RXN
• RHEA:23032
• Reactome:R-HSA-73810

Ontology

GO: Molecular Function    QuickGO    AmiGO