Search Ontology:
GO: Molecular Function

phospholipase A2 activity

Term ID
GO:0004623
Synonyms
  • cytosolic phospholipase A2 activity
  • lecithinase A activity
  • phosphatidase activity
  • phosphatidolipase activity
  • phosphatidylcholine 2-acylhydrolase activity
  • phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
  • phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
  • secreted phospholipase A2 activity
Definition
Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phospholipid + H2O = 1-acyl-sn-glycero-3-phospholipid + a fatty acid. This reaction removes the fatty acid attached to the sn2-position. Substrates include phosphatidylcholine, phosphatidylethanolamine, choline plasmalogen and phosphatides.
References
  • EC:3.1.1.4
  • MetaCyc:PHOSPHOLIPASE-A2-RXN
  • MetaCyc:RXN-15067
  • RHEA:15801
  • Reactome:R-HSA-1482604
  • Reactome:R-HSA-1482656
  • Reactome:R-HSA-1482679
  • Reactome:R-HSA-1482745
  • Reactome:R-HSA-1482759
  • Reactome:R-HSA-1482771
  • Reactome:R-HSA-1482776
  • Reactome:R-HSA-1482778
  • Reactome:R-HSA-1482816
  • Reactome:R-HSA-1482825
  • Reactome:R-HSA-1482856
  • Reactome:R-HSA-1482868
  • Reactome:R-HSA-1482884
  • Reactome:R-HSA-1482887
  • Reactome:R-HSA-1482897
  • Reactome:R-HSA-1482900
  • Reactome:R-HSA-1482907
  • Reactome:R-HSA-1602368
  • Reactome:R-HSA-1602374
  • Reactome:R-HSA-1602377
  • Reactome:R-HSA-1602398
  • Reactome:R-HSA-1602399
  • Reactome:R-HSA-1602417
  • Reactome:R-HSA-1602446
  • Reactome:R-HSA-8848484
Ontology
GO: Molecular Function    QuickGO    AmiGO
Relationships
is a type of
has subtype
negatively regulated by
positively regulated by
regulated by
Phenotype
Phenotype caused by Genes