phospholipase A2 activity

Term ID

GO:0004623

Synonyms

• cytosolic phospholipase A2 activity
• lecithinase A activity
• phosphatidase activity
• phosphatidolipase activity
• phosphatidylcholine 2-acylhydrolase activity
• phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
• phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
• secreted phospholipase A2 activity

Definition

Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phospholipid + H2O = 1-acyl-sn-glycero-3-phospholipid + a fatty acid. This reaction removes the fatty acid attached to the sn2-position. Substrates include phosphatidylcholine, phosphatidylethanolamine, choline plasmalogen and phosphatides.

References

• EC:3.1.1.4
• MetaCyc:PHOSPHOLIPASE-A2-RXN
• MetaCyc:RXN-15067
• RHEA:15801
• Reactome:R-HSA-1482604
• Reactome:R-HSA-1482656
• Reactome:R-HSA-1482679
• Reactome:R-HSA-1482745
• Reactome:R-HSA-1482759
• Reactome:R-HSA-1482771
• Reactome:R-HSA-1482776
• Reactome:R-HSA-1482778
• Reactome:R-HSA-1482816
• Reactome:R-HSA-1482825
• Reactome:R-HSA-1482856
• Reactome:R-HSA-1482868
• Reactome:R-HSA-1482884
• Reactome:R-HSA-1482887
• Reactome:R-HSA-1482897
• Reactome:R-HSA-1482900
• Reactome:R-HSA-1482907
• Reactome:R-HSA-1602368
• Reactome:R-HSA-1602374
• Reactome:R-HSA-1602377
• Reactome:R-HSA-1602398
• Reactome:R-HSA-1602399
• Reactome:R-HSA-1602417
• Reactome:R-HSA-1602446
• Reactome:R-HSA-8848484

Ontology

GO: Molecular Function    QuickGO    AmiGO