ribonuclease III activity

Term ID

GO:0004525

Synonyms

• pre-mRNA 3'-end processing endonuclease
• ribonuclease 3 activity
• RNase III activity

Definition

Catalysis of the endonucleolytic cleavage of RNA with 5'-phosphomonoesters and 3'-OH termini; makes two staggered cuts in both strands of dsRNA, leaving a 3' overhang of 2 nt. (2)

References

• EC:3.1.26.3
• MetaCyc:3.1.26.3-RXN
• Reactome:R-HSA-203862
• Reactome:R-HSA-203893
• Reactome:R-HSA-426464
• Reactome:R-HSA-9708292
• Reactome:R-HSA-9708408
• Reactome:R-HSA-9820840

Ontology

GO: Molecular Function    QuickGO    AmiGO