Search Ontology:

GO: Molecular Function

tryptophan 5-monooxygenase activity

Term ID

GO:0004510

Synonyms

indoleacetic acid-5-hydroxylase activity
L-tryptophan hydroxylase activity
L-tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating)
tryptophan 5-hydroxylase activity
tryptophan hydroxylase activity

Definition

Catalysis of the reaction: L-tryptophan + tetrahydrobiopterin + O2 = 5-hydroxy-L-tryptophan + 4-alpha-hydroxytetrahydrobiopterin + H2O. 1.14.16.4

References

EC:1.14.16.4
MetaCyc:TRYPTOPHAN-5-MONOOXYGENASE-RXN
RHEA:16709
Reactome:R-HSA-209828

Ontology

GO: Molecular Function QuickGO AmiGO

Relationships

is a type of: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen Show first 5 Terms
positively regulated by: tryptophan hydroxylase activator activity

tryptophan hydroxylase activator activity Show first 5 Terms

Phenotype

Phenotype caused by Genes