steroid 21-monooxygenase activity

Term ID

GO:0004509

Synonyms

21-hydroxylase activity
cytochrome P450 CYP21A1
cytochrome p450 XXIA1 activity
steroid 21-hydroxylase activity
steroid,hydrogen-donor:oxygen oxidoreductase (21-hydroxylating)

Definition

Catalysis of the reaction: A C(21) steroid + [reduced NADPH--hemoprotein reductase] + O2 = a 21-hydroxy-C(21)-steroid + [oxidized NADPH--hemoprotein reductase] + H2O.

References

EC:1.14.14.16
MetaCyc:STEROID-21-MONOOXYGENASE-RXN
RHEA:65612
Reactome:R-HSA-5601976

Ontology

GO: Molecular Function QuickGO AmiGO

Relationships

is a type of: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen steroid hydroxylase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen steroid hydroxylase activity Show first 5 Terms
has subtype: 17-hydroxyprogesterone 21-hydroxylase activity progesterone 21-hydroxylase activity

17-hydroxyprogesterone 21-hydroxylase activity progesterone 21-hydroxylase activity Show first 5 Terms

Phenotype

Phenotype caused by Genes