steroid 17-alpha-monooxygenase activity

Term ID

GO:0004508

Synonyms

• 17alpha-hydroxylase-C17,20 lyase activity
• cytochrome P-450 (P-45017alpha,lyase)
• cytochrome P450 CYP17
• cytochrome p450 XVIIA1 activity
• cytochrome P45017alpha
• steroid 17-alpha-hydroxylase activity
• steroid 17-alpha-hydroxylase-C17-20 lyase activity
• steroid 17-alpha-hydroxylase/17,20 lyase activity
• steroid 17alpha-hydroxylase activity
• steroid 17alpha-monooxygenase activity
• steroid 17alphahydroxylase/17,20 lyase activity
• steroid,hydrogen-donor:oxygen oxidoreductase (17alpha-hydroxylating)

Definition

Catalysis of the reaction: a C21-steroid + O2 + reduced [NADPH--hemoprotein reductase] = a 17alpha-hydroxy-C21-steroid + H+ + H2O + oxidized [NADPH--hemoprotein reductase].

References

• EC:1.14.14.19
• MetaCyc:STEROID-17-ALPHA-MONOOXYGENASE-RXN
• RHEA:65760
• Reactome:R-HSA-193068
• Reactome:R-HSA-193070
• Reactome:R-HSA-193072
• Reactome:R-HSA-193099
• Reactome:R-HSA-5601843
• Reactome:R-HSA-9035954
• Reactome:R-HSA-9035956

Ontology

GO: Molecular Function    QuickGO    AmiGO