Search Ontology:
GO: Molecular Function
calcidiol 1-monooxygenase activity
- Term ID
- GO:0004498
- Synonyms
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- 1-hydroxylase-25-hydroxyvitamin D3 activity
- 25-hydroxy D3-1alpha-hydroxylase activity
- 25-hydroxy vitamin D3 1-alpha-hydroxylase activity
- 25-hydroxycholecalciferol 1-hydroxylase activity
- 25-hydroxycholecalciferol 1-monooxygenase activity
- 25-hydroxycholecalciferol 1alpha-hydroxylase activity
- 25-hydroxycholecalciferol-1-hydroxylase activity
- 25-hydroxyvitamin D-1 alpha hydroxylase activity
- 25-hydroxyvitamin D3 1alpha-hydroxylase activity
- 25-OHD-1 alpha-hydroxylase activity
- calcidiol,NADPH:oxygen oxidoreductase (1-hydroxylating)
- cytochrome P450 CYP27B
- Definition
- Catalysis of the reaction: calcidiol + H+ + NADPH + O2 = calcitriol + H2O + NADP+. 1.14.15.18
- References
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- EC:1.14.15.18
- KEGG_REACTION:R03610
- MetaCyc:CALCIDIOL-1-MONOOXYGENASE-RXN
- RHEA:20573
- Reactome:R-HSA-209868
- Reactome:R-HSA-5602186
- Ontology
- GO: Molecular Function QuickGO AmiGO
- is part of
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- is a type of
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- negatively regulated by
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- positively regulated by
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- regulated by
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Phenotype
Phenotype caused by Genes