Search Ontology:
GO: Molecular Function

calcidiol 1-monooxygenase activity

Term ID
GO:0004498
Synonyms
  • 1-hydroxylase-25-hydroxyvitamin D3 activity
  • 25-hydroxy D3-1alpha-hydroxylase activity
  • 25-hydroxy vitamin D3 1-alpha-hydroxylase activity
  • 25-hydroxycholecalciferol 1-hydroxylase activity
  • 25-hydroxycholecalciferol 1-monooxygenase activity
  • 25-hydroxycholecalciferol 1alpha-hydroxylase activity
  • 25-hydroxycholecalciferol-1-hydroxylase activity
  • 25-hydroxyvitamin D-1 alpha hydroxylase activity
  • 25-hydroxyvitamin D3 1alpha-hydroxylase activity
  • 25-OHD-1 alpha-hydroxylase activity
  • calcidiol,NADPH:oxygen oxidoreductase (1-hydroxylating)
  • cytochrome P450 CYP27B
Definition
Catalysis of the reaction: calcidiol + H+ + NADPH + O2 = calcitriol + H2O + NADP+. 1.14.15.18
References
  • EC:1.14.15.18
  • KEGG_REACTION:R03610
  • MetaCyc:CALCIDIOL-1-MONOOXYGENASE-RXN
  • RHEA:20573
  • Reactome:R-HSA-209868
  • Reactome:R-HSA-5602186
Ontology
GO: Molecular Function    QuickGO    AmiGO
Relationships
is part of
is a type of
negatively regulated by
positively regulated by
regulated by
Phenotype
Phenotype caused by Genes