methylenetetrahydrofolate reductase (NAD(P)H) activity

Term ID

GO:0004489

Synonyms

• 5,10-CH(2)-H(4)folate reductase activity
• 5,10-CH2-H4folate reductase activity
• 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity
• 5,10-methylenetetrahydrofolate reductase (FADH) activity
• 5,10-methylenetetrahydrofolate reductase (FADH2) activity
• 5,10-methylenetetrahydrofolate reductase (NADPH) activity
• 5,10-methylenetetrahydrofolate reductase activity
• 5,10-methylenetetrahydrofolic acid reductase activity
• 5,10-methylenetetrahydropteroylglutamate reductase activity
• 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity
• 5-methyltetrahydrofolate:NAD oxidoreductase activity
• 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity
• 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity
• 5-methyltetrahydrofolate:NAD+ oxidoreductase activity
• 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity
• 5-methyltetrahydrofolate:NADP+ oxidoreductase activity
• MetF
• methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity
• methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity
• methylenetetrahydrofolate reductase (NADPH(2)) activity
• methylenetetrahydrofolate reductase (NADPH2)
• methylenetetrahydrofolate reductase [NAD(P)H]
• methylenetetrahydrofolate reductase activity
• methylenetetrahydrofolic acid reductase activity
• MTHFR activity
• N(5),N(10)-methylenetetrahydrofolate reductase activity
• N(5,10)-methylenetetrahydrofolate reductase activity
• N5,10-methylenetetrahydrofolate reductase activity
• N5,N10-methylenetetrahydrofolate reductase activity

Definition

Catalysis of the reaction: 5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H + H+. (2)

References

• EC:1.5.1.20
• KEGG_REACTION:R01224
• KEGG_REACTION:R07168
• MetaCyc:1.5.1.20-RXN
• Reactome:R-HSA-200676

Ontology

GO: Molecular Function    QuickGO    AmiGO