long-chain fatty acid-CoA ligase activity

Term ID

GO:0004467

Synonyms

• acyl-activating enzyme activity
• acyl-CoA ligase activity
• acyl-CoA synthetase activity
• fatty acid thiokinase (long-chain) activity
• LCFA synthetase activity
• lignoceroyl-CoA synthase activity
• long chain fatty acyl-CoA synthetase activity
• long-chain acyl CoA synthetase activity
• long-chain acyl-CoA synthetase activity
• long-chain acyl-coenzyme A synthetase activity
• long-chain fatty acid activation
• long-chain fatty acyl coenzyme A synthetase activity
• long-chain-fatty-acid-CoA ligase activity
• long-chain-fatty-acyl-CoA synthetase activity
• pristanoyl-CoA synthetase
• stearoyl-CoA synthetase
• thiokinase

Definition

Catalysis of the reaction: a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.

References

• EC:6.2.1.3
• MetaCyc:RXN-7904
• RHEA:15421
• Reactome:R-HSA-159425
• Reactome:R-HSA-192137
• Reactome:R-HSA-193401
• Reactome:R-HSA-193407
• Reactome:R-HSA-193424
• Reactome:R-HSA-193711
• Reactome:R-HSA-193727
• Reactome:R-HSA-193743
• Reactome:R-HSA-193766
• Reactome:R-HSA-201035
• Reactome:R-HSA-2046085
• Reactome:R-HSA-2046098
• Reactome:R-HSA-548843
• Reactome:R-HSA-5696004
• Reactome:R-HSA-9734535

Ontology

GO: Molecular Function    QuickGO    AmiGO