leukotriene-C4 synthase activity

Term ID

GO:0004464

Synonyms

• (7E,9E,11Z,14Z)-(5S,6R)-5,6-epoxyicosa-7,9,11,14-tetraenoate:glutathione leukotriene-transferase (epoxide-ring-opening)
• (7E,9E,11Z,14Z)-(5S,6R)-6-(glutathion-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate glutathione-lyase (epoxide-forming)
• leukotriene A(4):glutathione S-leukotrienyltransferase activity
• leukotriene A4:glutathione S-leukotrienyltransferase activity
• leukotriene C(4) synthetase activity
• leukotriene C4 synthetase activity
• leukotriene-C4 glutathione-lyase (leukotriene-A4-forming)
• LTC(4) synthase activity
• LTC(4) synthetase activity
• LTC4 synthase activity
• LTC4 synthetase activity

Definition

Catalysis of the reaction: leukotriene C(4) = glutathione + leukotriene A(4). 4.4.1.20

References

• EC:4.4.1.20
• KEGG_REACTION:R03059
• MetaCyc:LEUKOTRIENE-C4-SYNTHASE-RXN
• RHEA:17617
• Reactome:R-HSA-266050

Ontology

GO: Molecular Function    QuickGO    AmiGO