Search Ontology:
GO: Molecular Function

phosphatidylinositol phospholipase C activity

Term ID
GO:0004435
Synonyms
  • 1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity
  • 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity
  • 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase activity
  • monophosphatidylinositol phosphodiesterase activity
  • phosphatidylinositol-4,5-bisphosphate hydrolysis
  • phosphoinositidase C activity
  • phosphoinositide phospholipase C activity
  • PI-PLC activity
  • triphosphoinositide phosphodiesterase activity
Definition
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1,2-diacylglycerol + 1D-myo-inositol 1,4,5-trisphosphate + H+. 3.1.4.11
References
  • EC:3.1.4.11
  • KEGG_REACTION:R03435
  • MetaCyc:3.1.4.11-RXN
  • RHEA:33179
  • Reactome:R-HSA-111879
  • Reactome:R-HSA-167686
  • Reactome:R-HSA-1855177
  • Reactome:R-HSA-1855214
  • Reactome:R-HSA-1855221
  • Reactome:R-HSA-202407
  • Reactome:R-HSA-2730847
  • Reactome:R-HSA-5607735
  • Reactome:R-HSA-622382
  • Reactome:R-HSA-9032478
  • Reactome:R-HSA-9717205
Ontology
GO: Molecular Function    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes