Search Ontology:
GO: Molecular Function

hydroxymethylglutaryl-CoA reductase (NADPH) activity

Term ID
GO:0004420
Synonyms
  • 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity
  • HMG-CoA reductase activity
  • hydroxymethylglutaryl-CoA reductase activity
Definition
Catalysis of the reaction: (R)-mevalonate + CoA + 2 NADP+ = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H+ + 2 NADPH. 29224355
References
  • EC:1.1.1.34
  • KEGG_REACTION:R02082
  • MetaCyc:1.1.1.34-RXN
  • RHEA:15989
  • Reactome:R-HSA-191352
Ontology
GO: Molecular Function    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes