hydroxymethylglutaryl-CoA lyase activity

Term ID

GO:0004419

Synonyms

• (S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase (acetyl-CoA-forming)
• (S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase activity
• 3-hydroxy-3-methylglutarate-CoA lyase activity
• 3-hydroxy-3-methylglutaryl CoA cleaving enzyme
• 3-hydroxy-3-methylglutaryl coenzyme A lyase activity
• 3-hydroxy-3-methylglutaryl-CoA lyase activity
• HMG-CoA lyase activity
• hydroxymethylglutaryl coenzyme A lyase activity
• hydroxymethylglutaryl coenzyme A-cleaving enzyme

Definition

Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA. 4.1.3.4

References

• EC:4.1.3.4
• KEGG_REACTION:R01360
• MetaCyc:HYDROXYMETHYLGLUTARYL-COA-LYASE-RXN
• RHEA:24404
• Reactome:R-HSA-6788597
• Reactome:R-HSA-74180

Ontology

GO: Molecular Function    QuickGO    AmiGO