homocitrate synthase activity

Term ID

GO:0004410

Synonyms

• 2-hydroxybutane-1,2,4-tricarboxylate 2-oxoglutarate-lyase (CoA- acetylating) activity
• 2-hydroxybutane-1,2,4-tricarboxylate 2-oxoglutarate-lyase (CoA-acetylating)
• acetyl-CoA:2-oxoglutarate C-acetyltransferase (thioester-hydrolysing, carboxymethyl forming)
• acetyl-coenzyme A:2-ketoglutarate C-acetyl transferase activity
• homocitrate synthetase activity

Definition

Catalysis of the reaction: 2-oxoglutarate + acetyl-CoA + H2O = CoA + H+ + homocitrate.

References

• EC:2.3.3.14
• KEGG_REACTION:R00271
• MetaCyc:HOMOCITRATE-SYNTHASE-RXN
• RHEA:12929

Ontology

GO: Molecular Function    QuickGO    AmiGO