Search Ontology:
GO: Molecular Function

aspartic-type endopeptidase activity

Term ID
GO:0004190
Synonyms
  • aspartate protease activity
  • aspartic endopeptidase activity
  • aspartic protease activity
  • aspartyl protease activity
  • carboxyl protease activity
Definition
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile. 0198506732
References
  • EC:3.4.23.-
  • Reactome:R-HSA-157353
  • Reactome:R-HSA-157640
  • Reactome:R-HSA-2022403
  • Reactome:R-HSA-2022412
  • Reactome:R-HSA-2065357
  • Reactome:R-HSA-2220988
  • Reactome:R-HSA-373705
  • Reactome:R-HSA-9013361
  • Reactome:R-HSA-9017817
  • Reactome:R-HSA-9604294
Ontology
GO: Molecular Function    QuickGO    AmiGO
Relationships
is a type of
has subtype
negatively regulated by
Phenotype
Phenotype caused by Genes